Annex I – indicates if the substance is subject to PIC.

ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material. Values are generally displayed in milligram per kilo food. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Please note that the information provided in the free-text fields is not published in the brief profiles.

Dangerous Goods List (ADN, Chap. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. Properties of concern are calculated at four "levels" of certainty: The following properties of concern are calculated: The substance properties displayed in this section are derived from Harmonised classification and labelling (CLH) data, entries in the Candidate list of substances of very high concern for authorisation, the PBT assessment list, the ED assessment list, REACH registered dossier data and from notifications made under CLP. The five highest priority groupings of provided data are displayed in milligram per litre or molar per litre. This section summarises the density values from all registered dossiers for the substance. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. This directive requires employers to ensure proper signage is posted in areas where hazards cannot be avoided or reduced. VW denotes the form in which the substance is produced or placed on the market. Tumor formation is often observed in the spleen on prolonged administration. Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed. Bioaccumulation Factor (terrestrial species) L/kg ww provides substance information on the substance’s terrestrial bioaccumulative properties measured in litre per kilogram (wet weight). The brief profile is based on non-confidential data contained in ECHA’s databases at the time of generation. This product has been replaced by A8524-ALDRICH | Aniline hydrochloride ≥99%. Pricing & availability is not currently available. The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. If multiple values are available, the most conservative value (the highest percentage) is displayed. If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. The Agency thus cannot guarantee the correctness of the information displayed.

-021. This section displays the values related to carcinogenicity from all registered dossiers for the substance. According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed, causes serious eye irritation and may cause respiratory irritation.

In most cases, impurities constitute less than 10% of the substance. EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment, ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Endocrine disrupter testing in aquatic vertebrates – in vivo, Active/Inactive (pending). Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance.

Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. Prioritization by the dose descriptor type: Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. Warning! If the substance is classified under more than one CLH entry (e.g. Relative density at 20 °C provides information on the substance relative density at 20 °C.

For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. The source of the information is mentioned in the introductory sentence of the hazard statement. This Directive establishes rules for the safe transport of dangerous goods between EU countries by road, rail, and waterway. © 2020  Merck KGaA, Darmstadt, Germany and/or its affiliates. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton.